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Germany

Calorie-Burning "Switch" In Our Genes Determines Obesity

Researchers have discovered that a trigger in certain genes is responsible for some people burning calories better than others. In the long run, the finding may help in the fight against obesity.

In Montreal, destined since the womb.
In Montreal, destined since the womb.
Pia Heinemann

BERLIN A new study has found that a person's ability to burn calories is determined by the reaction of genes in the womb, which is largely fixed for life. Researchers nevertheless hope the findings can help in the global fight against obesity.

The discovery by the scientists in Germany may offer solace or further frustration for the some 2.1 billion obese and overweight people around the world. At the Max Planck Institute for Immunobiology and Epigenetics, researchers analyzed whether environmental factors play a role in weight gain. They found that when two mice with the exact same genetic makeup are fed the same things, some become obese and others don't, which suggests an epigenetic phenomenon; that is a difference in the way cells read genes.

The scientists looked at the genes of their subjects, discovering that a network of "imprinted genes" are the key to the weight differences. The scientists even succeeded in reducing the activity of those genes, resulting in an immediate effect on the weight of the mice.

It's at birth that the genes decide, like an interrupter that swtiches on, whether the mouse is going to be fat or not. And once the interrupter is activated, its body weight is largely predetermined for life.

An obesity study of twins has confirmed the theory. We may now be able to conclude that some people are genetically prone to obesity — and that this is decided during embryonic development.

Scientists now obviously want to discover whether the interrupter can be switched again, through a change of diet, stress reduction or medication.

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Society

Shakira, Miley Cyrus And The Double Standards Of Infidelity

Society judges men and women very differently in situations of adultery and cheating, and in divorce settlements. It just takes some high-profile cases to make that clear.

Photo of Bizarrap and Shakira for their song “Shakira: Bzrp Music Sessions, Vol. 53”
Mariana Rolandi

-Analysis-

BUENOS AIRES — When Shakira, the Colombian pop diva, divorced her soccer star husband Gerard Piqué in 2022, she wrote a song to overcome the hurt and humiliation of the separation from Piqué, who had been cheating on her.

The song, which was made in collaboration with Argentine DJ Bizarrap and broke streaming records, was a "healthy way of channeling my emotions," Shakira said. She has described it as a "hymn for many women."

A day after its launch, Miley Cyrus followed suit with her own song on her husband's suspected affairs. Celebrities and influencers must have taken note here in Argentina: Sofía Aldrey, a makeup artist, posted screenshots of messages her former boyfriend had sent other women while they were a couple.

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